Yesagyo ရေစကြိုမြို့
Town
Yesagyo Location in Burma
Coordinates: 21°38′00″N 95°14′29″E / 21.63333°N 95.24139°E / 21.63333; 95.24139
Country	Myanmar
Region	Magway Region
District	Pakokku District
Township	Yesagyo Township
Population  (2014 Cenus)
• Total	23,603
Time zone	UTC+6.30 (MST)

Yesagyo (Burmese: ရေစကြိုမြို့) is a town in the Magway Division in Myanmar. It is situated on the Chindwin River, near the site where it flows into Irrawaddy River. It is the principal town and administrative seat of Yesagyo Township.Yesagyo is a second biggest city of Pakokku District.

The town is served by the Chaung-U to Pakokku railway.