Shanley is a surname of Irish origin, anglicised from any of the following Gaelic phrases:

• Mac Seanlaoich meaning 'son of Seanlaoch'
• Ní Seanlaioch possibly meaning 'descendant of a daughter Seanlaoch'
• Nic Seanlaioch meaning 'daughter of Seanlaoch'
• Ó Seanlaoich possibly meaning 'descendant of a son of Seanlaoch'

• Bernard M. Shanley (1903–1992), associate of U.S. President Eisenhower
• Brian J. Shanley (born 1958), American priest of the Order of Preachers, president of Providence College
• Doc Shanley (1889–1934), American baseball player
• Eleanor Shanley, Irish vocalist
• Frank Shanley (1889–1917), English footballer
• Gib Shanley (1931–2008), American sports anchor/reporter
• James A. Shanley (1896–1965), American politician
• Jim Shanley (1854–1904), American baseball player
• Jim Shanley (American football) (1936–2019), American football player
• John Shanley (disambiguation), multiple people
• Mai Shanley (born c. 1963), American model
• Mary Shanley (1896–1989), New York City police detective
• Mary Lyndon Shanley (born 1944), feminist legal scholar
• Paul Shanley (1931–2020), American defrocked priest and convicted child-rapist

• Cal Shanley on US television series Studio 60 on the Sunset Strip, played by Timothy Busfield

• Shanley Allen, professor of linguistics
• Shanley Caswell (born 1991), American actress
• Shanley Del (born 1962), New Zealand musician
• Shanley Kane, American writer

• Shanley High School
• Shanley's Restaurants
• Shanley v. Northeast Independent School District
• The medieval Sept and Town of Mac Shanley, mentioned in the Irish Annals