Sena may refer to:

• Sanandaj or Sena, city in northwestern Iran
• Sena (state constituency), represented in the Perlis State Legislative Assembly
• Sena, a Medieval Catalan exonym for Siena, Italy
• Sena, Dashtestan, village in Bushehr Province, Iran
• Sena, Huesca, municipality in Huesca province, Spain
• Sena (Ibias), a parish in the municipality of Ibias
• Sena, Iran, village in Bushehr Province, Iran
• Sena Jan, village in Gandoman Rural District
• Sena Madureira, municipality located in the center of the Brazilian state of Acre
• Sena, New Mexico, unincorporated community and census-designated place
• Sena Nikhom, is a khwaeng (subdistrict) of Chatuchak district
• Sena Nikhom BTS station, is a BTS Skytrain station
• Sena Oura National Park, protected area with national park status in the African country of Chad
• Sena, Yemen is an ancient abandoned town in Yemen
• Sena (Kučevo) is a village in the municipality of Kučevo
• Seňa, village and municipality in the Kosice Region, Slovakia
• Vila de Sena or Sena, Mozambique

• Sezgi Sena Akay (born 1994), Turkish actress
• Sena (footballer) (born 1978), football manager and former player
• Sena I was King of Anuradhapura in the 9th century
• Sena II was a Sinhala King of Anuradhapura in the 9th century
• Sena III was King of Anuradhapura in the 10th century
• Sena IV was King of Anuradhapura in the 10th century
• Sena V was King of Anuradhapura in the 10th century
• Sena Acolatse (born 1990), American-Canadian professional ice hockey player
• Sena Can (born 2001), Turkish sport shooter
• Sena Elçin Karakaş (born 2004), Turkish trampoline gymnast
• Sena Hussain the lead singer of Secret Trial Five
• Sena Inami (井波 靖奈, born 1992), Japanese football player
• Sena Irie (入江 聖奈, born 2000), Japanese retired amateur boxer
• Sena Jeter Naslund (born 1942), American writer
• Sena Jurinac (1921–2011), Bosnian-born Austrian operatic soprano
• Sena Kana Japanese pop singer
• Sena Mahesh Patel Indian politician from Madhya Pradesh
• Sena Miyake (三宅 星南, born 2002), Japanese figure skater
• Sena Moon South Korean writer and translator
• Sena Nanayakkara Sri Lankan politician and academic
• Sena Nhavi Hindu saint-poet of the Varkari
• Sena Nur Çelik Turkish politician
• Sena Pavetić Croatian female basketball player
• Sena Ralte (born 1988) Indian professional footballer
• Sena Sakaguchi (阪口 晴南, born 1999), Japanese racing driver
• Sena Suzuki (鈴木 世奈, born 1991), Japanese ice hockey player
• Sena Takahashi (高橋 星名, born 2010), Japanese figure skater
• Sena Takano (髙野 芹奈, born 1998), Japanese sailor
• Sena Tomita (冨田 せな, born 1999), Japanese snowboarder
• Sena Yamada (山田 誓己, born 1994), Japanese Grand Prix motorcycle racer
• Yang Sena (양세나, born 1999), South Korean professional footballer
• Lady Tsukiyama also known as Sena (瀬名), Japanese samurai-class woman

• Balthasar Seña (1590–1614), Spanish Jesuit missionary
• Dominic Sena (born 1949), American movie director
• Gemma Sena Chiesa (1929–2024), Italian archaeologist
• Jacinto Roque de Sena Pereira (1784–1850), Portuguese-born Brazilian sailor notable
• James Sena (born 1988), Filipino professional basketball player
• João Victor Alves Sena (born 2000), or Neguinho, Brazilian futsal player
• Jun Sena (瀬奈じゅん, born 1974), Japanese actress
• Maryam Sena, wife of Sarsa Dengel, the Emperor of Ethiopia
• Suzanne Sena (born 1963), American television host

• Robin Sena from Witch Hunter Robin
• Sena Kobayakawa from Eyeshield 21
• Sena Hayami from Mashin Sentai Kiramager
• Kaito Sena from Torture Princess: Fremd Torturchen
• Sena from Xenoblade Chronicles 3

• Sena (film), Tamil-language crime film (2003)
• Sena/Quina, la inmortalidad del cangrejo, film written and directed by Paolo Agazzi.

• Sena (company), in Iceland
• Sena (wine), of Chile
• Sena dynasty, dynasty that ruled Bengal in the 11th and 12th centuries
• Sena and Guttika, Indian usurpers of the Anuradhapura throne in Sri Lanka
• Sena Kalyan Bhaban, is a 20-storied commercial building
• Sena Kalyan Sangstha, trust owned and operated by the Bangladesh Armed Forces.
• Sena language, language in central Mozambique
• Sena Medal, is awarded to members of the Indian army
• Sena Paribar Kalyan Samity, Bangladeshi non-profit operated by Bangladesh Army
• Sena people, ethnic group of Mozambique and Malawi
• Servicio Nacional de Aprendizaje or National Service of Learning, public institution of education in Colombia
• Sena (moth), a moth genus in the subfamily Lasiocampinae
• Sena railway, railway that connects Dondo, Mozambique, to Chipata, in Zambia
• Sena River, river of Bolivia
• Sena revolution of Bengal

• Amphoe Sena, district in Ayutthaya Province, Thailand
• Bangladesh Senabahini, the native name of the Bangladeshi Army
• Bharatiya Sena, the native name of the Indian Army
• Nepali Sena, the native name of the Nepalese Army
• Saena, city in Tuscany, Italy
• Sena de Luna, municipality in León province, Spain
• Senigallia, formerly Sena Gallica, Ancona, Italy
• Senna (disambiguation)
• Shanti Sena or Peace army, made up of Gandhi's followers in India
• Shiv Sena, political party in India
• Sena-Gahadavala Conflicts,a series of frequent expeditions of the Sena dynasty