E50
Route information
Length	5,100 km (3,200 mi)
Major junctions
West end	Brest, France
Major intersections	E05 Paris E15 Paris E25 Metz E35 (south of) Walldorf E45 Nuremberg E55 Prague E65 Prague E75 Trenčín E85 Ternopil E95 Uman E105 Novomoskovsk E40 Debaltseve E115 Rostov-na-Donu
East end	E119 Makhachkala, Russia
Location
Countries	France  Germany  Czech Republic  Slovakia  Ukraine  Russia
Highway system
International E-road network A Class B Class

European route E 50 is an A-type east–west connection across the European continent. It connects the key naval port of Brest in France with Makhachkala, on the Caspian Sea in the Russian republic Dagestan.

Half the route comprises highways and the other half provincial roads. The route is some 6,000 kilometres (3,700 mi) long and runs fully across the European continent.

On its way through Europe it crosses several major European routes, such as:

• E60 Brest–Vienna
• E5 Greenock-Algeciras
• E15 Inverness-Algeciras
• E45 Alta-Gela
• E75 Vardø-Pireas

It is one of the longest E roads on the continent.

Since 2014, parts of the road in eastern Ukraine have been under the control of the separatist Donetsk People's Republic and Lugansk People's Republic. During the 2022 Russian invasion of Ukraine, Russia took direct control of the areas in Donbas.

•  France
  • D 112: Brest ( E60) - Gouesnou
  • N 12: Gouesnou - Saint-Brieuc - Tramain ( E401) - Rennes
  • N 136: Rennes ( E3)
  • N 157: Rennes ( E3) - La Gravelle
  • A 81: La Gravelle - Laval - Le Mans ( E501)
  • A 11: Le Mans ( E501 E502) - Ablis
  • A 10: Ablis ( E5) - Massy ( E5 E15)
  • A 6b: Massy ( E5 E15) - Paris ( E15)
  • Boulevard Périphérique: Paris ( E15 E54)
  • A 4: Paris ( E15) - Reims ( E17 E46 E420) - Châlons-en-Champagne ( E17) - Metz ( E21 E23 E25) - Freyming-Merlebach ( E25)
  • A 320: Freyming-Merlebach ( E25) - Forbach
•  Germany
  • A 6 Saarbrücken ( E29 E422) - Mannheim ( E31 E35) - Heilbronn ( E41) - Feuchtwangen ( E43) - Nürnberg ( E45 E51 E56) - Waidhaus
•  Czech Republic
  • D 5: Rozvadov - Plzeň ( E49 E53) - Prague ( E48 E55)
  • D 0: Prague ( E48 E55 E59 E65)
  • D 1: Prague (Start of Concurrency with E59 E65) - Humpolec ( E551) - Jihlava (End of Concurrency with E59) - Brno ( E461 E462, End of Concurrency with E65)
  • I/50: Brno ( E462) - Starý Hrozenkov
•  Slovakia
  • I/9: Drietoma - Trenčín ( E572, Start of Concurrency with E75 )
  • D1: Trenčín ( E75 E572) - Žilina ( E442)
  • D3: Žilina
  • I/18: Žilina (End of Concurrency with E75) - Martin
  • D1: Martin
  • I/18: Martin - Ružomberok ( E77)
  • D1: Ružomberok - Prešov
  • I/18: Prešov ( E371)
  • I/20: Prešov
  • D1: Prešov - Bidovce
  • I/19: Bidovce ( E58 E71 E571) - Vyšné Nemecké
•  Ukraine (Note: since April 2021, M12 and M04 Stryi – Kropyvnytskyi – Debaltseve were combined into M30)^[1][2]
  • M 08: Uzhhorod border - Uzhhorod ( E573)
  • M 06: Uzhhorod ( E573) - Mukachevo ( E81 E471, End of Concurrency with E58) - Stryi ( E471)
  • M 12: Stryi ( E471) - Ternopil ( E85) - Khmelnytskyi - Vinnytsia ( E583) - Uman ( E95) - Kropyvnytskyi ( E584)
  • M 04: Kropyvnytskyi ( E584) - Oleksandriia ( E584) - Dnipro ( E105) - Donetsk - Debaltseve ( E40)
  • M 03: Debaltseve ( E40) - Dovzhansky
•  Russia
  • A 270: border with Ukraine - Novoshakhtinsk (Start of concurrency with E115)
  • M 4: Novoshakhtinsk - Rostov-on-Don ( E58) - Pavlovskaya (End of concurrency with E115)
  • R 217: Pavlovskaya ( E115) - Armavir - Mineralnye Vody ( E117) - Beslan ( E117) - Makhachkala ( E119)
  • Major towns along the R217 highway (Russia) include Kropotkin, Nevinnomyssk, Mineralnye Vody, Pyatigorsk, Nalchik, Beslan, Grozny, Gudermes, Khasavyurt, Makhachkala, and Derbent on the Caspian Sea. After skirting the Greater Caucasus, the route continues to Baku.

• UN Economic Commission for Europe: Overall Map of E-road Network (2007)

Geographic data related to European route E50 at OpenStreetMap