Men's singles
2022 San Diego Open
Final
Champion	Brandon Nakashima
Runner-up	Marcos Giron
Score	6–4, 6–4
Details
Draw	28 (4 Q / 3 WC )
Seeds	8
Events
Singles men women Doubles men women
← 2021 · San Diego Open

Brandon Nakashima defeated Marcos Giron in the final, 6–4, 6–4 to win the singles tennis title at the 2022 San Diego Open. It was his first ATP Tour title, and he won it in his hometown of San Diego.^[1]

Casper Ruud was the reigning champion,^[2] but competed at the Laver Cup instead.

The top four seeds received a bye into the second round.

	Semi-finals							Final
	1	Dan Evans	3	5
	3	Marcos Giron	6	7
								3	Marcos Giron	4	4
								5	Brandon Nakashima	6	6
	5	Brandon Nakashima	6	77
		Christopher O'Connell	4	63

	First round							Second round							Quarter-finals							Semi-finals
								1	D Evans	6	6
		T Daniel	6	6					T Daniel	4	4
	Q	Em Nava	4	3											1	D Evans	6	6
	WC	B Holt	7	65	3											C Lestienne	1	3
		C Lestienne	5	77	6				C Lestienne	6	6
		S Johnson	5	2				6	A Tabilo	1	3
	6	A Tabilo	7	6																		1	D Evans	3	5
																						3	M Giron	6	7
								3	M Giron	6	6
		TM Etcheverry	78	6					TM Etcheverry	4	3
	Q	F Mena	66	3											3	M Giron	77	6
	Q	C Eubanks	4	4											7	J Duckworth	65	3
	Q	M Krueger	6	6				Q	M Krueger	3	64
		A Popyrin	5	6	1			7	J Duckworth	6	77
	7	J Duckworth	7	4	6

	First round							Second round							Quarter-finals							Semi-finals
	5	B Nakashima	7	77
	WC	Z Svajda	5	65				5	B Nakashima	6	6
		D Kudla	6	6					D Kudla	3	4
	WC	F Verdasco	3	3											5	B Nakashima	6	4	6
		M-A Hüsler	3	5												DE Galán	3	6	4
		DE Galán	6	7					DE Galán	5	6	6
								4	P Martínez	7	1	4
																						5	B Nakashima	6	77
	8	J. J. Wolf	6	78																			C O'Connell	4	63
		S Kozlov	2	66				8	J. J. Wolf	3	5
		C O'Connell	4	6	0				C O'Connell	6	7
		J Kubler	6	3	0r											C O'Connell	6	4	7
		H Laaksonen	0	2											2	J Brooksby	4	6	5
		M McDonald	6	6					M McDonald	4	6	2
								2	J Brooksby	6	3	6

	First round							Qualifying competition
	1	Juan Pablo Ficovich	3	1
		Govind Nanda	6	6
									Govind Nanda	4	7	5
								5	Mitchell Krueger	6	5	7
	WC	Hudson Rivera	6	1	2
	5	Mitchell Krueger	3	6	6

	First round							Qualifying competition
	2	Facundo Mena	77	77
		Keegan Smith	61	62
								2	Facundo Mena	6	6
									Marek Gengel	3	4
		Marek Gengel	6	3	6
	8	Sebastian Fanselow	2	6	0

	First round							Qualifying competition
	3	Christopher Eubanks	6	77
	WC	Alafia Ayeni	1	63
								3	Christopher Eubanks	77	79
								6	Ernesto Escobedo	65	67
	PR	Bradley Klahn	6	66	2
	6	Ernesto Escobedo	3	78	6

	First round							Qualifying competition
	4	Emilio Nava	6	6
	Alt	Gage Brymer	1	1
								4	Emilio Nava	7	77
								7	Aleksandar Kovacevic	5	64
		Giovanni Oradini	65	2
	7	Aleksandar Kovacevic	77	6

• Main draw
• Qualifying draw