Singles
2021 Open Sud de France
Final
Champion	David Goffin
Runner-up	Roberto Bautista Agut
Score	5–7, 6–4, 6–2
Details
Draw	28 (4 Q / 3 WC )
Seeds	8
Events
Singles Doubles
← 2020 · Open Sud de France · 2022 →

Gaël Monfils was the defending champion,^[1] but chose not to defend his title.

With the loss of Ugo Humbert in the quarterfinals, this was the first tournament without a French champion since 2017 when Alexander Zverev won the title. It was also the first without a French finalist since 2004. David Goffin won the title, defeating Roberto Bautista Agut in the final, 5–7, 6–4, 6–2.

The top four seeds received a bye into the second round.

	Semifinals							Final
	1	Roberto Bautista Agut	7	6
	Q	Peter Gojowczyk	5	1
								1	Roberto Bautista Agut	7	4	2
								2	David Goffin	5	6	6
		Egor Gerasimov	4	6	4
	2	David Goffin	6	2	6

	First round							Second round							Quarterfinals							Semifinals
								1	R Bautista Agut	6	6
	Q	G Barrère	6	6				Q	G Barrère	0	3
		N Basilashvili	4	4											1	R Bautista Agut	6	6
	Q	T Griekspoor	6	65	6										6	U Humbert	3	3
		M Giron	2	77	3			Q	T Griekspoor	77	65	65
		N Gombos	3	63				6	U Humbert	64	77	77
	6	U Humbert	6	77																		1	R Bautista Agut	7	6
																						Q	P Gojowczyk	5	1
								3	D Lajović	65	5
		D Novak	77	1	6				D Novak	77	7
		G Simon	65	6	3											D Novak	4	1
		M Ymer	1	1											Q	P Gojowczyk	6	6
		J Veselý	6	6					J Veselý	77	64	3
	Q	P Gojowczyk	6	6				Q	P Gojowczyk	63	77	6
	8	J-L Struff	3	4

	First round							Second round							Quarterfinals							Semifinals
	5	J Sinner	6	2	63
		A Bedene	3	6	77				A Bedene	4	64
		E Gerasimov	710	6					E Gerasimov	6	77
	WC	A Murray	68	1												E Gerasimov	4	6	7
	Q	B Zapata Miralles	63	7	2											A Davidovich Fokina	6	4	5
		A Davidovich Fokina	77	5	6				A Davidovich Fokina	7	6
								4	H Hurkacz	5	2
																							E Gerasimov	4	6	4
	7	L Sonego	6	67	6																	2	D Goffin	6	2	6
	WC	H Gaston	3	79	1			7	L Sonego	6	6
		J-W Tsonga	4	2					S Korda	3	2
		S Korda	6	6											7	L Sonego	4	4
		L Pouille	66	2											2	D Goffin	6	6
	WC	B Bonzi	78	6				WC	B Bonzi	6	4	5
								2	D Goffin	4	6	7

	First round							Qualifying competition
	1	Kamil Majchrzak	6	4	4
		Lukáš Lacko	4	6	6
									Lukáš Lacko	2	1
								8	Peter Gojowczyk	6	6
		Maxime Janvier	0r
	8	Peter Gojowczyk	1

	First round							Qualifying competition
	2	Grégoire Barrère	2	6	6
		Quentin Halys	6	2	4
								2	Grégoire Barrère	4	6	6
									Botic van de Zandschulp	6	3	4
		Botic van de Zandschulp	6	7
	5	Arthur Rinderknech	2	5

	First round							Qualifying competition
	3	Antoine Hoang	6	6
	WC	Luca Van Assche	4	0
								3	Antoine Hoang	62	3
									Tallon Griekspoor	77	6
		Tallon Griekspoor	4	6	6
	6	Carlos Alcaraz	6	3	1

	First round							Qualifying competition
	4	Damir Džumhur	77	66	3
	WC	Kyrian Jacquet	64	78	6
								WC	Kyrian Jacquet	1	1
								7	Bernabé Zapata Miralles	6	6
		Sergiy Stakhovsky	1	0
	7	Bernabé Zapata Miralles	6	6

• Main draw
• Qualifying draw