Too Hot to Handle may refer to:

• Too Hot to Handle (1938 film), a 1938 film starring Clark Gable
• Too Hot to Handle (1950/1955), also known as Fig Leaf Frolics, a documentary film directed by burlesque impresario Lillian Hunt
• Too Hot to Handle (1960 film), a 1960 film starring Jayne Mansfield and directed by Terence Young, which was released in the United States with the title Playgirl After Dark
• Too Hot to Handle (1977 film), a 1977 action film starring Cheri Caffaro
• The Marrying Man, a 1991 film which was re-titled Too Hot to Handle in the UK and Australia

• "Too Hot to Handle", an episode of the 1973 Super Friends series
• "Too Hot to Handle", an episode of the 1987 Teenage Mutant Ninja Turtles animated series
• "Too Hot to Handle", an episode of The Super Mario Bros. Super Show!
• "Too Hot to Handle", an episode of The Dreamstone
• Too Hot to Handle (TV series), a 2020 Netflix original reality TV show.

• "Too Hot to Handle", a 1977 song by UFO on the album Lights Out
• Too Hot to Handle (Heatwave album), a 1977 album and track by Heatwave
• Too Hot to Handle (Jorma Kaukonen album), a 1985 album by Jorma Kaukonen

• Moonraker (novel), a 1955 James Bond novel renamed as Too Hot to Handle in the United States