Thick skin can refer to:

• The ability to withstand criticism.
• Literally thick skin covering the body of an animal, such as an elephant or rhinoceros.
• Callus, an area of thickened skin
  • Callus (disambiguation), similar uses of Callus such as a lack of empathy (callousness).
• Thick Skinned, a 1989 French film
• "Thick Skin", a song by Leona Lewis from I Am
• Thick Skin, a 2018 album by Tia Gostelow

• Pachyderm (disambiguation)