Scherf is a German surname. Notable people with the surname include:

• Charles Scherf (1917–1949), Australian flying ace of the Second World War
• Ferdinand Scherf (born 1943), German professor and historian
• Henning Scherf (born 1938), German lawyer and politician
• Lauren Scherf (born 1996), American basketball player
• Lindsey Scherf (born 1986), American long-distance runner

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