Protein-coding gene in the species Homo sapiens
Synaptotagmin-2 is a protein that in humans is encoded by the SYT2 gene .[ 5] [ 6]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000143858 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026452 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Jones JM, Popma SJ, Mizuta M, Seino S, Meisler MH (March 1995). "Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19". Mammalian Genome . 6 (3): 212– 3. doi :10.1007/BF00293017 . hdl :2027.42/47020 PMID 7749232 . S2CID 24653745 . ^ "Entrez Gene: SYT2 synaptotagmin II" .
Further reading
Fukuda M, Aruga J, Niinobe M, Aimoto S, Mikoshiba K (November 1994). "Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II" . The Journal of Biological Chemistry . 269 (46): 29206– 11. doi :10.1016/S0021-9258(19)62031-4 PMID 7961887 . Perin MS (October 1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin". Biochemistry . 35 (43): 13808– 16. doi :10.1021/bi960853x . PMID 8901523 . Baram D, Adachi R, Medalia O, Tuvim M, Dickey BF, Mekori YA, Sagi-Eisenberg R (May 1999). "Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells" . The Journal of Experimental Medicine . 189 (10): 1649– 58. doi :10.1084/jem.189.10.1649 . PMC 2193646 PMID 10330444 . Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms" . The Journal of Biological Chemistry . 275 (13): 9823– 31. doi :10.1074/jbc.275.13.9823 PMID 10734137 . Kida Y, Sakaguchi M, Fukuda M, Mikoshiba K, Mihara K (August 2000). "Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulum" . The Journal of Cell Biology . 150 (4): 719– 30. doi :10.1083/jcb.150.4.719 . PMC 2175286 PMID 10952998 . Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS (May 2001). "Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery" . The Journal of Cell Biology . 153 (5): 1111– 20. doi :10.1083/jcb.153.5.1111 . PMC 2174325 PMID 11381094 . Kida Y, Sakaguchi M, Fukuda M, Mikoshiba K, Mihara K (November 2001). "Amino acid residues before the hydrophobic region which are critical for membrane translocation of the N-terminal domain of synaptotagmin II" . FEBS Letters . 507 (3): 341– 5. doi :10.1016/S0014-5793(01)03000-9 PMID 11696368 . S2CID 29026112 . Lindmark IM, Karlsson A, Serrander L, Francois P, Lew D, Rasmusson B, Stendahl O, Nüsse O (June 2002). "Synaptotagmin II could confer Ca(2+) sensitivity to phagocytosis in human neutrophils". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research . 1590 (1– 3): 159– 66. doi :10.1016/S0167-4889(02)00209-4 . PMID 12063179 . Rickman C, Archer DA, Meunier FA, Craxton M, Fukuda M, Burgoyne RD, Davletov B (March 2004). "Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate" . The Journal of Biological Chemistry . 279 (13): 12574– 9. doi :10.1074/jbc.M310710200 PMID 14709554 . Lee BH, Min X, Heise CJ, Xu BE, Chen S, Shu H, Luby-Phelps K, Goldsmith EJ, Cobb MH (September 2004). "WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding" . Molecular Cell . 15 (5): 741– 51. doi :10.1016/j.molcel.2004.07.018 PMID 15350218 .
