Protein-coding gene in the species Homo sapiens
Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene .[ 5]
The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.[ 5]
See also
References
Further reading
McIntire SL, Reimer RJ, Schuske K, et al. (1997). "Identification and characterization of the vesicular GABA transporter". Nature . 389 (6653): 870– 6. doi :10.1038/39908 . PMID 9349821 . S2CID 4404823 . Kleiderlein JJ, Nisson PE, Jessee J, et al. (1999). "CCG repeats in cDNAs from human brain". Hum. Genet . 103 (6): 666– 73. doi :10.1007/s004390050889 . PMID 9921901 . S2CID 23696667 . Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20" . Nature . 414 (6866): 865– 71. Bibcode :2001Natur.414..865D . doi :10.1038/414865a PMID 11780052 . Chessler SD, Simonson WT, Sweet IR, Hammerle LP (2002). "Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets" . Diabetes . 51 (6): 1763– 71. doi :10.2337/diabetes.51.6.1763 PMID 12031963 . Jellali A, Stussi-Garaud C, Gasnier B, et al. (2002). "Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina" . J. Comp. Neurol . 449 (1): 76– 87. doi :10.1002/cne.10272 PMID 12115694 . S2CID 27646744 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Geigerseder C, Doepner R, Thalhammer A, et al. (2003). "Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors" . Neuroendocrinology . 77 (5): 314– 23. doi :10.1159/000070897 . hdl :11336/36231 PMID 12806177 . S2CID 7652352 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 .
By group
SLC1–10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21–30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31–40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41–48
(41): (42): (43): (44): (45): (46): (47): (48):
Transporter
GAT Tooltip GABA transporter VIAAT Tooltip Vesicular inhibitory amino acid transporter
Enzyme
GAD Tooltip Glutamate decarboxylase GABA-T Tooltip γ-Aminobutyrate aminotransferase
Other
