Pistol Pete may refer to:

• Frank Eaton (1860–1958), American scout, Indian fighter and cowboy
• Peter Handscomb (born 1991), Australian cricketer
• Pete Loncarevich (born 1966), American former bicycle (BMX) racer
• Pete Maravich (1947–1988), American basketball player
• Pete Reiser (1919–1981), American baseball player
• Peter Rollack (born c. 1974), founder and leader of the Bronx-based street gang Sex Money Murda
• Pete Sampras (born 1971), American tennis player
• Peter Smith (curler) (born 1964), Scottish curler
• Leon Dorsey (1975–2008), American serial killer; nicknamed "Pistol Pete" while incarcerated

• Pistol Pete (New Mexico State University), the mascot for New Mexico State University athletics
• Pistol Pete (Oklahoma State University), the mascot for Oklahoma State University–Stillwater athletics
• Pistol Pete (University of Wyoming), the mascot for University of Wyoming athletics

• Pete (Disney), a Disney character, and nemesis of Mickey Mouse, once known by the alias 'Pistol Pete'
• the daughter of Pete on the Disney animated television series Goof Troop
• nickname of a Japanese Type 92 10 cm cannon captured by the Americans in World War II
• Pistol Pete, a sitcom pilot created by John Swartzwelder
• Pistol Pete's Pizza, a defunct Arizona restaurant chain bought out by Peter Piper Pizza