Organ is a surname. Notable people with the surname include:

• Bryan Organ (born 1935), English painter
• Diana Organ (born 1952), British politician
• Ellen Organ (1903–1908), Irish child venerated by some Roman Catholics
• Felix Organ (born 1999), English cricketer
• Gerry Organ (born 1944), Canadian football player
• Lawrence P. Organ (born 1959), Canadian businessman
• Marjorie Organ (1886–1930), Irish-born American illustrator, cartoonist, caricaturist and model for her painter husband Robert Henri
• Michael Organ (born 1956), Australian politician
• Michael Organ (drummer) (born 1953), American drummer
• Stuart Organ (1951–2024), British actor
• Tommy Organ (born 1963), American musician
• Tyne-James Organ (born 1995), Australian alternative rock singer and songwriter