Helen Brown may refer to:

• Helen Agcaoili Summers Brown (1915–2011), Filipino-American teacher, librarian, and founder of the Pilipino American Reading Room and Library
• Helen Brown (artist) (1917–1986), New Zealand artist
• Helen Brown (author) (born 1954), New Zealand author
• Helen Evans Brown (1904–1964), American food writer and cookbook author
• Helen Gurley Brown (1922–2012), American author, publisher, and businesswoman
• Helen Hayes (née Brown, 1900–1993), American actress
• Helen Jean Brown (1903–1982), American botanist and phycologist
• Helen Gilman Brown (1867–1942), American philanthropist
• Helen Lawrenson (1907–1982), American writer, born Helen Strough Brown
• Helen McElhone, née Brown (1933–2013), Scottish politician
• Helen Paxton Brown (1876–1956), Scottish artist
• Helen Shaw (politician) (1879–1964), Scottish politician, born Helen Brown Shaw
• Phyllis Fraser (1916–2006), American actress, journalist, and children's book publisher, born Helen Brown Nichols