Donald Mitchell may refer to:

• Donald Mitchell (writer) (1925–2017), British writer on music
• Donald Grant Mitchell (1822–1908), American essayist and novelist
• Donald J. Mitchell (1923–2003), congressman from New York
• Donald Mitchell (American football) (born 1976), Tennessee Titans football player
• Donald O. Mitchell, American sound engineer
• Donald Mitchell (weightlifter) (1955–2010), Australian Olympic weightlifter

• Don Mitchell (disambiguation)