William Tucker may refer to:

• William Tooker or Tucker (1557/58–1621), English churchman
• William Tucker (musician) (1961–1999), guitar player
• William Tucker (politician) (1843–1919), member of the New Zealand Legislative Council
• William Tucker (priest) (1856–1934), Anglican archdeacon and dean
• William Tucker (settler) (1784–1817), convict, sealer, trader in human heads, Otago settler, New Zealand's first art dealer
• William Eldon Tucker (1872–1953), England international rugby union player
• William Ellis Tucker (died 1832), American porcelain manufacturer
• William F. Tucker (1827–1881), Confederate States Army brigadier general
• William G. Tucker (born 1935), modernist British sculptor
• William H. Tucker (American politician) (1825–1866), Wisconsin state senator
• William H. Tucker (baseball) (1819–1894), American baseball pioneer
• William H. Tucker (psychologist) (born 1940), professor of psychology
• William Jewett Tucker (1839–1926), president of Dartmouth College
• William Sansome Tucker (1877–1955), English physicist known for his sound mirrors
• Bill Tucker (American football) (1942–2015), American football player
• Bill Tucker (rugby union) (1903–1991), England international rugby union player
• William Tucker (Jamestown immigrant) (1588–1643/44), settled in Jamestown of the Colony of Virginia
• William Tucker (Virginia colony) (1624–?), born to two of the first Africans in Virginia