William Goodwin may refer to:

• William Goodwin (priest) (died 1620), English academic and Anglican Dean of Christ Church
• William Watson Goodwin (1831–1912), American classical scholar
• William S. Goodwin (1866–1937), U.S. Representative from Arkansas
• W. A. R. Goodwin (William Archer Rutherfoord Goodwin, 1869–1939), American Episcopal clergy
• Billy Goodwin (1892–1951), English footballer with Manchester United
• Bill Goodwin (Welsh footballer) (1892–1972), footballer with Crewe Alexandra F.C.
• William Nelson Goodwin (1909–1975), U.S. federal judge
• Bill Goodwin (1910–1958), American radio presenter
• Bill Goodwin (jazz drummer) (born 1942), American musician
• Will Goodwin (footballer) (born 2002), English footballer
• William Goodwin (runner), winner of the two miles at the 1927 USA Indoor Track and Field Championships

• William Gradwell-Goodwin (died 1942), mayor of Newcastle-under-Lyme, Staffordshire, England
• Bill Godwin (fl. 1950s–1980s), Rhodesian army officer
• William Godwin (disambiguation)