William Bassett may refer to:

• William Bassett (by 1531–52 or later),^{[clarification needed]} MP for Maldon
• William Bassett (died 1553), MP for Derbyshire
• William Bassett (died 1586) (1507–1586), MP for Glamorgan
• William Bassett (died 1601), MP for Staffordshire
• William Bassett (Royalist) (died 1656), MP for Bath
• William Bassett (d. 1667), early New England colonist
• William Bassett (died 1693) (1628–1693), MP for Bath
• William Bassett Jr. (1624–1703), whose daughter Elizabeth Proctor was accused of witchcraft in the 1692 Salem witch trials
• William H. Bassett (born 1935), American actor
• William Bassett (USAF officer), a USAF officer who, contrary to a received order, decided not to launch missiles armed with nuclear warheads while stationed at Okinawa during the 1962 Cuban Missile Crisis

• William Basset (disambiguation)
• Billy Bassett (1869–1937), English footballer, director and club chairman for West Bromwich Albion
• Billy Bassett (Welsh footballer) (1912–1977)