West Virginia Route 46
Route information
Maintained by WVDOH
Length	32.0 mi[1] (51.5 km)
Western section
Length	11.9 mi[2] (19.2 km)
West end	WV 42 in Elk Garden
East end	MD 135 near Beryl
Eastern section
Length	20.9 mi[2] (33.6 km)
West end	MD 36 / MD 135 in Piedmont
Major intersections	US 220 in Keyser
East end	WV 28 in Fort Ashby
Location
Country	United States
State	West Virginia
Counties	Mineral
Highway system
West Virginia State Highway System Interstate US State
← WV 45 → WV 47

West Virginia Route 46 is an east–west state highway split into two segments in Mineral County, West Virginia, United States. The western terminus of the western segment is at West Virginia Route 42 in Elk Garden. The eastern terminus is at the Maryland state line north of Beryl, where WV 46 crosses the Potomac River and intersects Maryland Route 135 on the north bank.

The western terminus of the eastern segment is at the Maryland state line in Piedmont, where WV 46 continues into Maryland as Maryland Route 36. The eastern terminus is at West Virginia Route 28 in Fort Ashby.

The two segments are connected by a two-mile (3 km) portion of MD 135 and MD 36 in Maryland's Allegany County.

• Jennings Randolph Lake

County	Location	mi[2]	km	Destinations	Notes
Mineral	​	0.0	0.0	WV 42 – Mount Storm, Kitzmiller, MD
North Branch Potomac River				Beryl Bridge
		11.9	19.2	MD 135	Maryland state line
Gap in route
North Branch Potomac River		0.0	0.0	MD 36 north / MD 135	Maryland state line
				Westernport Bridge
Mineral	Keyser	5.2	8.4	US 220 (Mineral Street) to US 50 – Cumberland, MD, Moorefield	interchange westbound; intersection eastbound
	Fort Ashby	20.9	33.6	WV 28 / CR 15 (Dans Run Road) – Cumberland, MD, Romney
1.000 mi = 1.609 km; 1.000 km = 0.621 mi