Protein-coding gene in the species Homo sapiens
Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene .[ 5] [ 6] [ 7]
Interactions WD repeat-containing protein 77 has been shown to interact with CTDP1 [ 8] Protein arginine methyltransferase 5 .[ 5]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000116455 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000561 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G (Mar 2002). "A novel WD repeat protein component of the methylosome binds Sm proteins" . J Biol Chem . 277 (10): 8243– 7. doi :10.1074/jbc.M109984200 PMID 11756452 . ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem . 236 (1): 107– 13. doi :10.1006/abio.1996.0138 . PMID 8619474 . ^ "Entrez Gene: WDR77 WD repeat domain 77" .^ Licciardo P, Amente Stefano, Ruggiero Luca, Monti Maria, Pucci Piero, Lania Luigi, Majello Barbara (Feb 2003). "The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP" . Nucleic Acids Res . 31 (3). England: 999– 1005. doi :10.1093/nar/gkg197 . PMC 149217 PMID 12560496 .
Further reading
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1– 2): 171– 4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353– 8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1– 2): 149– 56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Licciardo P, Amente S, Ruggiero L, et al. (2003). "The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP" . Nucleic Acids Res . 31 (3): 999– 1005. doi :10.1093/nar/gkg197 . PMC 149217 PMID 12560496 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 PMID 14702039 . Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene . 23 (35): 5901– 11. doi :10.1038/sj.onc.1207782 . PMID 15221005 . S2CID 3114318 . Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" . Curr. Biol . 14 (16): 1436– 50. doi :10.1016/j.cub.2004.07.051 PMID 15324660 . S2CID 2371325 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Amente S, Napolitano G, Licciardo P, et al. (2005). "Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation" . FEBS Lett . 579 (3): 683– 9. doi :10.1016/j.febslet.2004.12.045 PMID 15670829 . Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1" . Nature . 441 (7091): 315– 21. Bibcode :2006Natur.441..315G . doi :10.1038/nature04727 PMID 16710414 . Furuno K, Masatsugu T, Sonoda M, et al. (2006). "Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro". Biochem. Biophys. Res. Commun . 345 (3): 1051– 8. doi :10.1016/j.bbrc.2006.05.014 . PMID 16712789 . Zhou L, Wu H, Lee P, Wang Z (2007). "Roles of the androgen receptor cofactor p44 in the growth of prostate epithelial cells" . J. Mol. Endocrinol . 37 (2): 283– 300. doi :10.1677/jme.1.02062 PMID 17032745 . Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635– 48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Liang JJ, Wang Z, Chiriboga L, et al. (2007). "The expression and function of androgen receptor coactivator p44 and protein arginine methyltransferase 5 in the developing testis and testicular tumors". J. Urol . 177 (5): 1918– 22. doi :10.1016/j.juro.2007.01.017 . PMID 17437848 .
External links Overview of all the structural information available in the PDB for UniProt : Q9BQA1 PDBe-KB . 
