Vernon or Vern Smith may refer to:

• Vern Smith (journalist) (1892–?), American left-wing journalist
• Vernon C. Smith (1892–1963), American politician from Virginia
• Vernon B. Smith (1894–1969), American regional artist
• Vernon Smith (American football) (1908–1988), American football, basketball, and baseball player and coach
• Vernon L. Smith (born 1927), American economist
• Vernon Smith (Indiana politician) (born 1944)
• Vernon Smith (basketball) (1958–1992), American basketball player
• Vern Smith (ice hockey) (born 1964), Canadian ice hockey defenceman
• Vernon K. Smith (died 1966), Idaho politician
• Vernon Smith (screenwriter) (active 1924–1951), writer of American films