Two Medicine River
Amtrak's Empire Builder crosses the Two Medicine River near East Glacier Park in 2011.
Montana rivers with Two Medicine in the north central
Location
Country	Pondera and Glacier County, Montana
Physical characteristics
Source
• coordinates	48°29′32″N 113°15′49″W / 48.49222°N 113.26361°W / 48.49222; -113.26361 (Two Medicine River)[1]
Mouth
• coordinates	48°29′11″N 112°13′40″W / 48.48639°N 112.22778°W / 48.48639; -112.22778 (Two Medicine River)[1]
• elevation	3,294 feet (1,004 m)[1]
Discharge
• location	Browning
• average	375 cu ft/s (10.6 m3/s)[2]
Basin features
River system	Missouri River

The Two Medicine River is a tributary of the Marias River, approximately 60 mi (97 km) long, in northwestern Montana in the United States.

It rises in the Rocky Mountain Front in Glacier National Park at the continental divide and flows east, down from the mountains and across the Blackfeet Indian Reservation. It receives Birch Creek in southeastern Glacier County and joins Cut Bank Creek to form the Marias, approximately 12 mi (19 km) southeast of Cut Bank.

• List of rivers of Montana
• Montana Stream Access Law