Tsugaru (津軽) may refer to:

• Tsugaru, Aomori, a city of Aomori Prefecture, Japan
• Tsugaru Peninsula
• Tsugaru Strait, between Honshū and Hokkaidō
  • Tsugaru Kaikyō Ferry, a ferry crossing this strait
• Tsugaru-jamisen, a traditional style of shamisen playing associated with the area
• Tsugaru dialect, a dialect of Japanese spoken in this area
• Tsugaru clan, a daimyō clan
• Tsugaru (novel), by Osamu Dazai
• Tsugaru Expressway, an expressway in Aomori Prefecture, Japan
• Tsugaru (train), a train service in Japan
• Japanese cruiser Tsugaru (formerly the Imperial Russian Pallada), a warship in the Imperial Japanese Navy
• Japanese minelayer Tsugaru, a minelayer that took part in the Pacific War
• "Tsugaru", a song from the Dance Dance Revolution series
• Tsugaru Mine, an extensive coal mine in Kobyaysky Ulus, Sakha Republic, Siberia
• Tsugaru (apple), a variety of Japanese apple