TUBE1
| TUBE1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | TUBE1, TUBE, dJ142L7.2, tubulin epsilon 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 607345; MGI: 1919174; HomoloGene: 17762; GeneCards: TUBE1; OMA:TUBE1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.[5] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000074935 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019845 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Tubulin, epsilon 1".
Further reading
- Chang P, Giddings TH, Winey M, Stearns T (January 2003). "Epsilon-tubulin is required for centriole duplication and microtubule organization". Nature Cell Biology. 5 (1): 71–6. doi:10.1038/ncb900. PMID 12510196. S2CID 1318660.
- Zanic M, Stear JH, Hyman AA, Howard J (October 2009). May RC (ed.). "EB1 recognizes the nucleotide state of tubulin in the microtubule lattice". PLOS ONE. 4 (10): e7585. Bibcode:2009PLoSO...4.7585Z. doi:10.1371/journal.pone.0007585. PMC 2761489. PMID 19851462.
- Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. doi:10.1038/71350. PMID 10620804. S2CID 23500269.