TERC may refer to:

• Telomerase RNA component, a human gene.
• TERC (Cambridge, Massachusetts), a nonprofit research and development organization in Cambridge, Massachusetts, the developers of the Investigations in Numbers, Data, and Space mathematics curriculum
  • "Investigations" or TERC, a K–5 mathematics curriculum, developed at TERC (Cambridge, Massachusetts)
• Technical Education Research Centers (TERC)
• CSIRO Tropical Ecosystems Research Centre
• Terrestrial Environment Research Center. A research center at University of Tsukuba.
• Thermal Enclosure Rater Checklist A standard for achieving green building certification in the Energy Star home rating program.
• UC Davis Tahoe Environmental Research Center (TERC). A non-profit organization that conducts research on Lake Tahoe and educated the public on environmental issues at Lake Tahoe