Sweet is an Anglo-Saxon surname. Notable people with the surname include:

• Alec Stone Sweet, Yale Law School professor, musician and pétanque player
• Alanson Sweet (1804–1891), American businessman and politician
• Apollo Sweet (born 1957), Samoan/Australian boxer of the 1980s and '90s
• Blanche Sweet (1896–1986), silent film actress
• Brad Sweet (born 1985), American race car driver
• Burton E. Sweet (1867–1957), American politician from Iowa
• Darrell Sweet (musician) (1947–1999), co-founder and drummer of the band Nazareth
• Darrell K. Sweet (1934–2011), American illustrator
• David Sweet (disambiguation)
• Denise Sweet, Native American poet and academic, appointed Poet Laureate of Wisconsin in 2004
• Devin Sweet (born 1996), American baseball player
• Dolph Sweet (1920–1985), American actor
• Don Sweet (born 1948), former Canadian Football League kicker
• Elnathan Sweet (1837–1903), New York State Engineer and Surveyor 1884–1887
• Edwin F. Sweet (1847–1935), U.S. Representative from Michigan
• Gary Sweet (born 1957), Australian film and television actor
• George Sweet (1844–1920), English-born Australian geologist
• George Sweet (football manager) (1897–1969), Scottish football manager
• Dita Von Teese (born Heather Renée Sweet in 1972), American burlesque performer
• Henry Sweet (1845–1912), English philologist, phonetician and grammarian
• Herbert J. Sweet (1919–1998), United States Marine Corps official
• John Sweet (disambiguation)
• Jonathan Sweet, Australian actor
• Leonard Sweet (born 1961), American author, preacher, and United Methodist clergyman
• Lynn Sweet (born 1961), American journalist and columnist
• Lynn Sweet (American football) (1881–1918), American football player
• Matthew Sweet (born 1964), American alternative rock musician
• Melissa Sweet, Australian human health and medicine journalist
• Melissa Sweet (born 1956), American children's illustrator who won the 2012 Sibert Medal
• Michael Sweet (disambiguation)
• Ossian Sweet (1895–1960), African-American physician charged with, but not convicted of, murder for defending himself against a white mob
• Rachel Sweet (born 1962), American singer, writer and actress
• Robert Sweet (disambiguation)
• Roland Andrew Sweet (1940–2019), American mathematician and computer scientist
• Samuel Sweet (1825–1886), English-Australian settler and photographer
• Sylvanus H. Sweet (1830–1899), New York State Engineer and Surveyor 1874–1875
• Thaddeus C. Sweet (1872–1928), American politician from New York politician
• Walter C. Sweet (1927–2015), American paleontologist
• William Sweet (disambiguation)
• Willis Sweet (1856–1925), American politician from Idaho