St. Nicholas Cathedral, or variations on the name, may refer to buildings dedicated to Saint Nicholas in the following places:

• Cathedral of St Nicholas, which in 1571 became the Lala Mustafa Pasha Mosque in Famagusta, Cyprus
• St. Nicholas Cathedral (Almaty), Kazakhstan
• St. Nicholas Cathedral (Seoul), South Korea
• St. Nicholas Cathedral (Dushanbe), Tajikistan
• St. Nicholas Cathedral, Da Lat, Vietnam

• St. Nicholas Cathedral, Feldkirch, Austria
• Cathedral of St Nicholas, which in 1571 became the Lala Mustafa Pasha Mosque in Famagusta, Cyprus
• Cathedral of St Nicholas, České Budějovice, Czech Republic
• St Nicholas Cathedral, a former church in Igaliku, Greenland; its remains are now the Garðar Cathedral Ruins
• Church of Saint Nicholas, the Palmi Cathedral, Italy
• St Nicholas Naval Cathedral, Karosta, Latvia
• Saint Nicholas Cathedral, Monaco
• St. Nicholas Cathedral, Ruski Krstur, Serbia
• Saint Nicholas Cathedral, Trnava, Slovakia
• Saint Nicholas Cathedral, Ljubljana, Slovenia
• St. Nicholas of Bari Concathedral, Alicante, Spain
• Cathedral of St Nicholas, the Fribourg Cathedral, Switzerland
• Cathedral Church of St Nicholas, the Newcastle Cathedral, in Newcastle upon Tyne, United Kingdom

• St Nicolas Church, the former name until 1917 of the Finnish Evangelical Lutheran Helsinki Cathedral
• Saint Nicholas Cathedral, Kuopio

• Orthodox Cathedral of St. Nicholas, Białystok
• Cathedral of St. Nicholas, Bielsko-Biała
• St. Martin and St. Nicholas Cathedral, Bydgoszcz
• St. Nicholas Cathedral, Elbląg
• Cathedral of St. Nicholas, the seat of the Roman Catholic Diocese of Kalisz

• St. Andrew and St. Nicholas Orthodox Cathedral, Galați
• St. Nicholas Cathedral, Oradea
• Cathedral of Saint Nicholas, Râmnicu Vâlcea, the seat of the archdiocese of Râmnic
• St. Nicholas Cathedral, Tulcea

• St. Nicholas Military Cathedral in Kyiv
• St. Nicholas Roman Catholic Cathedral, Kyiv

• St Nicholas Russian Orthodox Cathedral, Brisbane, Queensland, Australia

• St Nicholas Cathedral, a former church in Igaliku, Greenland; its remains are the Garðar Cathedral Ruins
• St. Nicholas Cathedral, Tumbes, Peru
• Cathedral of St. Nicholas, Caracas, Venezuela, an Eastern Orthodox church serving the Russian-Venezuelan community

• St. Nicholas Cathedral (Chicago), Illinois
• St. Nicholas Russian Orthodox Cathedral (Manhattan), New York City
• St. Nicholas Cathedral (Washington, D.C.)
• Saint Nicholas Russian Orthodox Cathedral (Seattle), a Seattle landmark

• Saint Nicholas's Church (disambiguation)
• Basilica of Saint Nicholas (disambiguation)