The 6th St. Louis Film Critics Association Awards were announced on 15 December and awarded on December 21, 2009.

• George Clooney – Up in the Air
• Jeff Bridges – Crazy Heart
• Ben Foster – The Messenger
• Morgan Freeman – Invictus
• Patton Oswalt – Big Fan
• Jeremy Renner – The Hurt Locker

• Carey Mulligan – An Education
• Saoirse Ronan – The Lovely Bones
• Maya Rudolph – Away We Go
• Gabourey Sidibe – Precious
• Meryl Streep – Julie and Julia

• Up
• Coraline
• The Fantastic Mr. Fox
• Ponyo
• The Princess and the Frog

• Nine – Dion Beebe
• The Hurt Locker – Barry Ackroyd
• Inglourious Basterds – Robert Richardson
• Red Cliff (Chi bi) – Lü Yue and Zhang Li
• A Single Man – Eduard Grau
• Where the Wild Things Are – Lance Acord

• Kathryn Bigelow – The Hurt Locker
• Wes Anderson – The Fantastic Mr. Fox
• Oren Moverman – The Messenger
• Jason Reitman – Up in the Air
• Quentin Tarantino – Inglourious Basterds

• Capitalism: A Love Story
• Anvil! The Story of Anvil
• Food, Inc.
• Good Hair
• Tyson

• Up in the Air
• (500) Days of Summer
• An Education
• The Hurt Locker
• Invictus
• Precious
• Up

• The Hangover
• (500) Days of Summer
• Away We Go
• Pirate Radio
• Zombieland

• Red Cliff (Chi bi) • China
• The Baader Meinhof Complex (Der Baader Meinhof Komplex) • Germany
• Coco Before Chanel (Coco avant Chanel) • France
• The Maid (La nana) • Chile
• Treeless Mountain • South Korea
• Without Name (Sin nombre) • Spain

• Nine
• Crazy Heart
• Pirate Radio
• The Princess and the Frog
• Up

• (500) Days of Summer – Scott Neustadter and Michael H. Weber
• An Education – Nick Hornby
• The Hurt Locker – Mark Boal
• Inglourious Basterds – Quentin Tarantino
• Up in the Air – Jason Reitman and Sheldon Turner

• Christoph Waltz – Inglourious Basterds
• Robert Duvall – The Road
• Woody Harrelson – The Messenger
• Alfred Molina – An Education
• Stanley Tucci – The Lovely Bones

• Mo'Nique – Precious
• Marion Cotillard – Nine
• Vera Farmiga – Up in the Air
• Anna Kendrick – Up in the Air
• Mélanie Laurent – Inglourious Basterds
• Samantha Morton – The Messenger

• Avatar
• District 9
• The Lovely Bones
• Star Trek
• Where the Wild Things Are

• Avatar
• (500) Days of Summer
• District 9
• The Fantastic Mr. Fox
• The Lovely Bones

• Up – "Opening marriage montage"
• (500) Days of Summer – "'Expectations vs. reality' split-screen sequence"
• (500) Days of Summer – "'Morning after' dance number"
• Inglourious Basterds – "The opening farmhouse scene"
• Precious – "Mo'Nique's scene at social worker office"