Tom Dooley or Thomas Dooley may refer to:

• Tom Dula (1845–1868), American figure of folk legend hanged in North Carolina for murder
  • "Tom Dooley" (song), American folksong based upon the above incident
  • The Legend of Tom Dooley (1959), film starring Michael Landon, based on the folk song

• Thomas Anthony Dooley III (1927–1961), American humanitarian who worked in Laos and Vietnam
• Thomas Dooley (born 1961), retired German-American footballer
• Thomas E. Dooley, American media executive
• Thomas P. Dooley, Judeo-Christian author, biomedical scientist, inventor
• Tom Dooley (American football) (1934–2018), American football official
• Tom Dooley (racewalker) American race walker at the 1968 and 1972 Olympics
• Tom Dooley (editor) (born 1970), American magazine editor
• Tom Dooley (footballer) (1914–1975), English footballer

• Thomas Dooley Elementary School, Illinois