Joe may refer to:

In politics:

• Joe Clark, the 16th Prime Minister of Canada
• Uncle Joe, the leader of the Soviet Union from the mid-1920s to his death in 1953

In sports:

• Joe Crede Third Baseman for the Chicago White Sox
• Joe Cole, footballer
• Joe Kelly (Formula One), famous formula one driver from Dublin, Ireland
• Joe Montana, quarterback
• Joe Thomas, offensive tackle for the Wisconsin Badgers
• Joe Thornton, ice hockey center
• Samoa Joe, profesional wrestler

In television:

• Average Joe, reality TV dating shows that aired on the NBC network
• Joe Menosky, the Star Trek writer credited with starting the trend of working the number 47 into every script
• Joe Piscopo, American comedian known for his work on Saturday Night Live

In music:

• Joe (singer), an R&B singer
• Joe Perry, guitarist for Aerosmith
• Joe Strummer, co-founder and lead singer of punk rock band The Clash, and later, The Mescaleros

In Soviet weapon testing:

• Joe 1, the first Soviet nuclear weapon test
• Joe 4, the first Soviet test of a thermonuclear weapon

In fiction:

• Joe, 1970 film starring Peter Boyle as the title character
• Joe, the name of the Doctor in Star Trek: Voyager in one possible future
• Joe Higashi, one of the lone wolves from the Fatal Fury and King of Fighters Saga.
• Joe Kido, one of the main characters in the popular anime Digimon Adventure
• Joe Swanson, a recurring character in Family Guy
• Joe Yabuki, anti-hero protagonist of legendary boxing comic Ashita no Joe(aka "Tomorrow's Joe").
• Viewtiful Joe, the main hero of the Viewtiful Joe series

In generic naming:

• Joe Cool, nickname given primarily to those who display a calm or placid attitude
• Joe Bloggs, commonly used placeholder name in United Kingdom teaching, programming, and other thinking and writing
• Joe Sixpack, generic name in the United States to denote a hypothetical member of society deemed a "common man"
• Joe Sacco, comics journalist born in Malta.

In other fields:

• Joe, nickname for coffee derived from the name of Secretary of the Navy Josephus Daniels
• Joe FM, a brand for several radio stations in North America
• Joe job, spam designed to look like it is coming from someone else
• Joe Van Holsbeeck, a youth who was murdered by a mugger in a Brussels subway station
• Joe's Own Editor, a Unix text editor

• Joseph