Talk:HIV: Difference between revisions
2602:304:787a:37d9:66b9:e8ff:feb8:6554 (talk) →Edit request on 27 July 2013: new section |
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[[Special:Contributions/2602:304:787A:37D9:66B9:E8FF:FEB8:6554|2602:304:787A:37D9:66B9:E8FF:FEB8:6554]] ([[User talk:2602:304:787A:37D9:66B9:E8FF:FEB8:6554|talk]]) 05:52, 27 July 2013 (UTC) |
[[Special:Contributions/2602:304:787A:37D9:66B9:E8FF:FEB8:6554|2602:304:787A:37D9:66B9:E8FF:FEB8:6554]] ([[User talk:2602:304:787A:37D9:66B9:E8FF:FEB8:6554|talk]]) 05:52, 27 July 2013 (UTC) |
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:Good work, to be sure, from a fine group of investigators, but the article already covers the range of mechanisms for CD4+ T-cell depletion. Adding such detail from a lone primary publication might strike some as [[WP:UNDUE|undue]], even if our [[WP:MEDRS|sourcing policies]] encouraged use of primary sources. Thanks for the request, though. Do others have thoughts on this proposed edit? [[User:Keepcalmandcarryon|Keepcalmandcarryon]] ([[User talk:Keepcalmandcarryon|talk]]) 13:10, 29 July 2013 (UTC) |
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Edit request on 13 December 2011
To whomever it may concern,
I am a student in a Neuropsychology course at Boston University. My professor has previously contacted the administrators of this page to attain permission to add a section. We would truly appreciate if you would review and add the section we would like to contribute. Please let us know what changes are necessary.
Thank you so much.
adding section to see refs
Dr. Francoise Barre-Sinoussi
Why is Dr. Francoise Barre-Sinoussi not listed as a co-discoverer of HIV? She won the 2008 Nobel Prize in Physiology for this along with Luc Montagnier. (http://www.cnn.com/2013/06/04/health/lifeswork-barre-sinoussi/index.html?hpt=hp_t3) Encyclopedia1742 (talk) 15:41, 4 June 2013 (UTC)
lymph?
I would think that lymph would be infectious, but it's not mentioned. Might be relevant for people with edema. — kwami (talk) 17:46, 10 June 2013 (UTC)
- Do you have a source that says that somebody was exposed to lymph and got infected? Ruslik_Zero 19:16, 10 June 2013 (UTC)
- No. Just a question. And if it's not infectious, that would be worth mentioning. — kwami (talk) 02:12, 12 June 2013 (UTC)
- If interstitial fluid weeps from a wound in a person with edema, what comes out is composed very much like plasma, with which it is essentially (not exactly) in equilibrium. Thus, interstitial fluid has a level of HIV similar to blood (since plasma is the acellular portion of blood). I'm not sure how we would incorporate this into the article in a way that is well-sourced and of due weight. -- Scray (talk) 02:56, 12 June 2013 (UTC)
- Just to anticipate potential confusion: Universal precautions apply to any body fluid that is difficult to differentiate from blood, and if interstitial fluid is seeping from a wound it would be hard to differentiate it from blood. In contrast, sweat is specifically excluded from universal precautions as a non-infectious body fluid. This adds to my misgivings about adding this information to our article. -- Scray (talk) 03:11, 12 June 2013 (UTC)
- If interstitial fluid weeps from a wound in a person with edema, what comes out is composed very much like plasma, with which it is essentially (not exactly) in equilibrium. Thus, interstitial fluid has a level of HIV similar to blood (since plasma is the acellular portion of blood). I'm not sure how we would incorporate this into the article in a way that is well-sourced and of due weight. -- Scray (talk) 02:56, 12 June 2013 (UTC)
- No. Just a question. And if it's not infectious, that would be worth mentioning. — kwami (talk) 02:12, 12 June 2013 (UTC)
- I couldn't find a source that describes investigation of the infectious capacity of lymph. Much of the literature about HIV & lymph is related to either tuberculosis or lymphoma. Axl ¤ [Talk] 09:27, 12 June 2013 (UTC)
Controversy
There is some controversy as to if HIV causes AIDS, you should include a subsection for it to be complete. — Preceding unsigned comment added by 173.218.151.8 (talk) 19:27, 18 July 2013 (UTC)
- There is no controversy. TechBear | Talk | Contributions 19:45, 18 July 2013 (UTC)
Edit request on 20 July 2013
Please remove "safe sex" and replace with "safer sex." 24.151.70.251 (talk) 08:15, 20 July 2013 (UTC)
Not done:. It's called Safe sex. See WP:COMMONNAME. RudolfRed (talk) 15:27, 20 July 2013 (UTC)
Edit request on 27 July 2013
A recent study proposed "abortive infection" as a new mechanism for CD4 T-cell depletion by HIV-1. Using a physiologicaly relevant experimental system formed with fresh human lymphoid cultures, Doitsh et Al. demonstrated that CD4 T cells are not dying because of a toxic action of products encoded by HIV. Rather, these CD4 T cells are dying as a consequence of a powerful defense response launched against the virus before it can make copies of itself. HIV enters the CD4 T cells that are destined to die and begins to make a DNA copy of its RNA, a process called reverse transcription. However, during this process, incomplete DNA intermediates that accumulate in the cytoplasm are sensed by an unknown mechanism and trigger the cell to ‘commit suicide’ in an attempt to protect the host from spread of the virus [1]. While this response is likely designed to be protective, HIV subverts and amplifies it so effectively that it becomes a central driver of HIV pathogenesis. 2602:304:787A:37D9:66B9:E8FF:FEB8:6554 (talk) 05:52, 27 July 2013 (UTC)
- Good work, to be sure, from a fine group of investigators, but the article already covers the range of mechanisms for CD4+ T-cell depletion. Adding such detail from a lone primary publication might strike some as undue, even if our sourcing policies encouraged use of primary sources. Thanks for the request, though. Do others have thoughts on this proposed edit? Keepcalmandcarryon (talk) 13:10, 29 July 2013 (UTC)