Southern Italian may refer to:

• Anything of or from Southern Italy or the Mezzogiorno
• The Neapolitan language, a language group native to Southern Italy
• The Calabrian language, a language group native to Southern Italy
• Extreme Southern Italian, a language group native to Southern Italy
  • The Salentino dialect, a dialect native to Salento
  • The Sicilian language, a language native to Sicily
• Southern Italian Koiné, a koiné language native to Southern Italy

• South Italy, a statistical region
• Southern Italy (European Parliament constituency)