Shaikh usually refers to:

• Sheikh, as an alternate Romanization; a term for elders, tribal leaders, and royalty in Arabic-influenced cultures

It may also refer to:

• Shaikhs in South Asia, a social and ethnic grouping in South Asia
• Kashmiri Shaikhs, a large Kashmiri clan
• Gujarati Shaikh, a Muslim community found in the state of Gujarat
• Punjabi Shaikhs, a community found in Punjab consisting of Muslim converts from the Brahmins, Rajputs, and Khatris castes
• Shaikhs of Rajasthan, a Muslim community found in the state of Rajasthan
• Shaikhs of Uttar Pradesh
• Sindhi Shaikhs, a community found in Sindh consisting Muslim converts from the Lohana caste

• Anwar Shaikh (critic of Islam) (1928–2006), Pakistani-born British author
• Anwar Shaikh (economist) (born 1945), Pakistani American economist
• Fatima Sana Shaikh (born 1992), Indian actress
• Shaikh Aasif Shaikh Rashid Indian politician

• Shaik (disambiguation)