Scotti is a surname of Italian origin. Notable persons with that surname include:

• Andrea Scotti (born 1931), Italian film and television actor
• Andrés Scotti (born 1975), Uruguayan football (soccer) player
• Antonio Scotti (1866–1936), Italian operatic baritone
• Ben Scotti (born 1937), American football (American football) player
• Carlo Scotti (born 1904), Italian boxer
• Diego Scotti (born 1977), Uruguayan football (soccer) player
• Francesco Scotti (born 1983), Italian footballer
• Friedrich von Scotti (1889-1969), general of Nazi Germany during World War II
• Gianbernardino Scotti (died 1568), Italian Roman Catholic bishop and cardinal
• Gian Giacomo Gallarati Scotti (1886-1983), Italian politician, 5th podestà of Milan
• Giovanni Scotti (1911-1992), Italian ice hockey player
• Gottardo Scotti (1447-1481), Italian painter of the Renaissance period
• James V. Scotti (born 1960), American astronomer
• Lemmo Rossi-Scotti, count (1848-1926), Italian late-Romantic painter, mainly of battle scenes
• Luigi Scotti (born 1932), Italian judge and minister of justice
• Michael Scotti, (born 1963), American football player
• Mike Scotti, former U.S. Marine and author
• Mikhail Scotti (1812–1861), Russian painter
• Nick Scotti (born 1966), American actor and singer
• Ottavio Scotti (1904-1975), Italian art director
• Pasquale Scotti (born 1958), Italian criminal and boss of the Camorra
• Piero Scotti (1909–1976), Italian racing driver
• Ranuccio Scotti Douglas (1597-1659), Bishop of Borgo San Donnino, Apostolic Nuncio to Switzerland and France
• Roger Scotti (1925–2001), French football player
• Tino Scotti (1905–1984), Italian actor
• Tommaso Scotti (died 1556), Italian bishop of Terni
• Tony Scotti (born 1939), American actor and producer
• Umberto Scotti (fl. 1885–1904), one of the first players of Italian side A.C. Milan
• Vincenzo Scotti (born 1933), Italian politician and government minister
• Vito Scotti (1918–1996), American actor

• Scotti family