Schottenstein may refer to:

• Melvin L. Schottenstein (1932-1993), American Jewish Entrepreneur and Community Leader in Columbus, Ohio having founded a Law Practice and a Public National Homebuilding Company, M/I Homes
• Eduard Schott von Schottenstein [de] (1822–1897), German civil servant
• Jerome Schottenstein (1926–1992), American Jewish entrepreneur and philanthropist
• Karl Schott von Schottenstein [de] (1792–1882), Württemberg politician
• Konrad Schott von Schottenstein [de] (d. 1526), Margravial Bailiff and Burgrave of Rothenberg
• Lutz Schott von Schottenstein [de] (d. 1484), Frankish nobleman
• Max Schott von Schottenstein (1836–1917), Württemberg general and minister

• House of Schott von Schottenstein [de], a German noble family

• Schottenstein's, former American department store chain
• Jerome Schottenstein Center, multi-purpose arena on the campus of Ohio State University, in Columbus, Ohio
• Schottenstein Stores Corp., Columbus, Ohio, a holding company

• Schottenstein campus, the future building of the Israel Antiquities Authority
• The Schottenstein Talmud
• Schottenstein Prize in Cardiovascular Sciences
• Schottenstein Center, Ohio 2005, 2015 live album by Bruce Springsteen
• Nuremberg v. Konrad Schott von Schottenstein