Sastry may refer to:

• Ajay Sastry (born 1975), director and writer
• Ann Marie Sastry, American engineer, educator, and businessperson
• Arvind Sastry (born 1990), screenwriter
• B. V. K. Sastry (1916–2003), writer and music critic
• Bhagavatula Sadasiva Shankara Sastry
• Chellapilla Satyanarayana Sastry
• Chellapilla Venkata Sastry (1870–1950), Telugu language poet laureate and scholar
• Devudu Narasimha Sastri (1895–1962), Kannada writer, novelist, Sanskrit scholar, ritualist, actor and journalist
• Devulapalli Krishnasastri (1887–1980), Telugu poet, playwright, and translator
• Dhulipala Seetarama Sastry (1921–2007)
• Divakarla Tirupati Sastry (1872–1920), Telugu language poet and scholar
• Emani Sankara Sastry (1922–1987), Veena player of Carnatic music
• Gangadhara Sastry (born 1967), Indian singer and composer
• Garikapati Narahari Sastry (born 1966), Indian chemist
• J. C. M. SastryIndian (1936–2005), Nephrologist .
• Jandhyala Papayya Sastry (1912–1992), Telugu writer and lyricist
• Jandhyala Subramanya Sastry Indian film screenwriter, director and actor
• K. N. T. Sastry (1945–2018), National Award-winning Telugu film director.
• Kaliakudi Natesa Sastry, exponent of Harikatha
• Kapali Sastry (1886–1953), Sanskrit scholar, author, translator, and disciple of Sri Aurobindo
• Kasibhatta Brahmaiah Sastry (1863–1940), Sanskrit and Telugu scholar
• Madhunapantula Satyanarayana Sastry (1920–1992), poet
• Malladi Chandrasekhara Sastry (1925–2022), scholar and television personality
• Malladi Ramakrishna Sastry (1905–1965), Telugu writer
• Melattur Venkatarama Sastry (1770–1830), Telugu poet and playwright
• Mokkapati Narasimha Sastry (1892–1973), Indian Telugu language novelist
• Murali Sastry (born 1959), Indian scientist
• Panchagnula Adinarayana Sastry (1890–1951)
• Patrayani Seetharama Sastrya singer, teacher and music composer of Andhra
• Penumarti Viswanatha Sastry (1929–1998), Telugu writer and editor
• Podili Brahmayya Sastry
• Puranam Srinivasa Sastry (born 1953), Indian writer
• R. V. S. Peri Sastri, former Chief Election Commissioner of India
• Rachakonda Viswanatha Sastry (1922–1993), writer of in Telugu literature
• Ramajogayya Sastry (born 1970), Indian Telugu lyricist
• Ramayanam Sarveswara Sastry (1889–1962), actor
• Rambhatla Lakshminarayana Sastry (1908–1995), Telugu and Sanskrit scholar
• Ravi Shastri (born 1962), Indian Cricketer
• S. Shankar Sastry, Dean of the College of Engineering at the University of California, Berkeley.
• Savitha Sastry (born 1969), Bharatanatyam Dancer
• Sirivennela Sitaramasastri
• Sosale Garalapury Sastry (1899–1955), Indian industrial chemist
• Srikanth Sastry, Boston University Professor awarded the Shanti Swarup Bhatnagar
• Sripada Krishnamurty Sastry (1866–1960), poet
• Sripada Subrahmanya Sastry (1891–1961), Telugu writer from Andhra Pradesh
• Trilochan Sastry, former Dean at Indian Institute of Management, Bangalore
• Tripuraribhatla Ramakrishna Sastry (1914–1998), actor
• V. Kutumba Sastry (born 1950), Indian academic. He was the Vice-Chancellor of the Rashtriya Sanskrit Sansthan.
• Veda Archana Sastry, Indian film actress
• Vedam Venkataraya Sastry (1853–1929), Sanskrit and Telugu poet and critic
• Vedantam Ramalinga Sastry, Indian classical dancer in Kuchipudi
• Veluri Venkata Krishna Sastry, archaeologist and historian in Andhra Pradesh
• Vuppuluri Ganapathi Sastry (1898–1989), Indian Sanskrit scholar, writer, and spiritual teacher

• Sastri
• Sastry automorphism, in mathematics, an automorphism of a field of characteristic 2
• Sastry number, in mathematics, an integer n so that n concatenated with (n+1) is an integer square number.^[1]
• Shastry