RUC may refer to:

• Rádio Universidade de Coimbra or Coimbra University Radio, a Portuguese university station
• Rapid Update Cycle, an atmospheric prediction system
• Renmin University of China, Beijing
• Road User Charges (RUC), taxes payable in New Zealand
• Roskilde University or Roskilde Universitetscenter
• Royal Ulster Constabulary, the police force in Northern Ireland from 1922 to 2001
• Specialty Society Relative Value Scale Update Committee, for US healthcare pricing

Ruc may refer to:

• Chut language in Vietnam, also known as Ruc or Ruc-Sach
• Rục people