Quadruple may refer to:

• 4-tuple, an ordered list of elements, with four elements
• Quad (figure skating), a figure skating jump
• Quadruple (computing), a term used as alternative for nibble in some contexts
• Quadruple-precision floating-point format in computing
• Multiple birth with four offspring
• A term for winning four football trophies in a single season

• 4 (disambiguation)
• Quadruple Alliance (disambiguation), any of a number of military alliances
• Quadruple glazing, a type of insulated glazing
• Quadrupel, a strong beer
• Quadripole
• Quadrupole