Project Genesis may refer to:

• Project Genesis (Star Trek), a fictional technology from the Star Trek universe
• Project Genesis (organization), an Orthodox Jewish outreach organization that teaches Judaism on the Internet
• A project by Royal Caribbean International to develop their latest cruise ships—the Oasis-class cruise ship
• An alternate name for the TV series Deepwater Black
• Toyota Project Genesis, a 1999 plan to attract more youthful buyers
• Genesis (Final Fantasy character), a character in the Compilation of Final Fantasy VII
• Genesis Device, an LGPL licensed game engine
• Norton 360, codenamed Project Genesis or simply Genesis
• Project Genesis, a collaborative project between Freightliner, UK and General Electric for a main line freight locomotive, subsequently named PowerHaul
• Project Genesis, a demo (computer-based audio-visual work of art) by Hungarian demogroup Conspiracy
• Project Genesis (ESA), a program of the ESA to increase earth observation satellites accuracy to within 1 mm and a long-term stability of 0.1 mm/year.
• Genesis Project, conceptual low-cost interstellar mission aiming to establish a biosphere on other planets

• Genesis (disambiguation)