Pagels is a surname. Notable people with the surname include:

• Elaine Pagels (born 1943), American theologian
• Eva Pagels (born 1954), German field hockey player
• Georges-Guillaume Pagels (1855–1897), Swedish officer in the service of the International African Association
• Heinz Pagels (1939–1988), American physicist
• Tietje Spannenburg-Pagels (1906 - after 1933), Dutch speed skater

• Pagel, a surname