Two-spirit (also two spirit or twospirit) refers to Native Americans who fulfill one of many mixed gender roles found traditionally among many North American indigenous groups. Traditionally the roles included wearing the clothing and performing the work of both male and female genders. The term usually implies a masculine spirit and a feminine spirit living in the same body and was coined by contemporary LGBT Native Americans to describe themselves and the traditional roles they are reclaiming. There are many terms for these individuals in various indigenous languages. As of 1991, male and female bodied Two-Spirit people have been "documented in over 130 tribes, in every region of North America, among every type of native culture".

Sophie performing in 2018

Sophie Xeon (/ˈziːɒn/; 17 September 1986 – 30 January 2021), known mononymously as SOPHIE (stylized in all caps), was an English music producer, songwriter, and DJ. Her work is known for its brash take on pop music and is distinguished by experimental sound design, "sugary" synthesized textures, and incorporation of underground dance styles. She would help pioneer the 2010s hyperpop microgenre.

Sophie rose to prominence with a string of breakthrough singles led by "Bipp" (2013); these were compiled on the singles collection Product (2015). She concealed her identity early in her solo career, but came out publicly as transgender in 2017. The following year, Sophie released the studio album Oil of Every Pearl's Un-Insides, earning a nomination for the Grammy Award for Best Dance/Electronic Album. She worked closely with artists from the PC Music label, including A. G. Cook and GFOTY, and also produced for acts such as Charli XCX, Vince Staples, Kim Petras, Madonna, Hyd, Gaika, and Namie Amuro.

• ... that the portrayal of a transgender child by Sofía Otero made her the youngest actor to win the Silver Bear for Best Leading Performance?
• ... that Anjali Lama, Nepal's first transgender model, worked with Calvin Klein in 2019?
• ... that since 2018, IKEA's stuffed toy shark Blåhaj has become a popular Internet meme and an icon of the online transgender community?
• ... that the British musician Charlie Deakin Davies cofounded the Trans Creative Collective, a directory of transgender musicians?
• ... that The Cock Destroyers released a trans-inclusive sex education video for Netflix before hosting Slag Wars: The Next Destroyer?
• ... that Sarah Ashton-Cirillo, covering the Russian invasion of Ukraine, said that Ukrainians care less about her being transgender than Americans do?

• 2 – Lynn Conway (1938-2024), American computer scientist and transgender activist
• 3 – Raewyn Connell (1944), Australian transgender sociologist
• 5 – Roxen (2000), Romanian non-binary singer
• 7 – Michaela Jaé Rodriguez (1991), American actress and singer
• 10 – Jeffrey Catherine Jones (1944-2011), American transgender artist
• 13 – Masha Gessen (1967), Russian trans non-binary journalist
• 15 – Jamie Clayton (1978), American actress and model
• 26 – Yoon Ha Lee (1979), American author

• ... that African-American gay and transgender youth Ali Forney, once homeless himself, had a homeless LGBT youth center in New York City named after him for his work helping other youths?
• ... that non-binary transgender actor Indya Moore became the first transgender person to be featured on the cover of the US version of Elle magazine when they were featured in May 2019?
• ... that Jennie June (b. 1874), one of the earliest transgender people to publish an autobiography in the US, published the first and second volumes in 1918 and 1922, and wrote a third volume which was discovered in 2010?

The misconception of equating ease of life with “passing” must be dismantled in our culture. The work begins by each of us recognizing that cis people are not more valuable or legitimate and that trans people who blend as cis are not more valuable or legitimate. We must recognize, discuss, and dismantle this hierarchy that polices bodies and values certain ones over others. We must recognize that we all have different experiences of oppression and privilege, and I recognize that my ability to blend as cis is one conditional privilege that does not negate the fact that I experience the world as a trans woman (with my own fears, insecurities, and body-image issues) no matter how attractive people may think I am.