Protein-coding gene in the species Homo sapiens
Olfactory receptor 2C1 is a protein that in humans is encoded by the OR2C1 gene .[ 5] [ 6]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[ 6]
Ligands
See also
References
^ a b c GRCh38: Ensembl release 89: ENSG00000168158 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059043 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Centola M, Chen X, Sood R, Deng Z, Aksentijevich I, Blake T, Ricke DO, Chen X, Wood G, Zaks N, Richards N, Krizman D, Mansfield E, Apostolou S, Liu J, Shafran N, Vedula A, Hamon M, Cercek A, Kahan T, Gumucio D, Callen DF, Richards RI, Moyzis RK, Doggett NA, Collins FS, Liu PP, Fischel-Ghodsian N, Kastner DL (Jan 1999). "Construction of an ~700-kb Transcript Map Around the Familial Mediterranean Fever Locus on Human Chromosome 16p13.3" . Genome Res . 8 (11): 1172–91. doi :10.1101/gr.8.11.1172 . PMC 310791 PMID 9847080 . ^ a b "Entrez Gene: OR2C1 olfactory receptor, family 2, subfamily C, member 1" .^ a b Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire" . Science Signaling . 2 (60): ra9. doi :10.1126/scisignal.2000016 . PMC 2774247 PMID 19261596 .
Further reading
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family" . Proc. Natl. Acad. Sci. U.S.A . 101 (8): 2584–9. Bibcode :2004PNAS..101.2584M . doi :10.1073/pnas.0307882100 PMC 356993 PMID 14983052 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 .
External links
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
Class I
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Class IItetrapod specific receptors)
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