ODF is the OpenDocument format, a standard for electronic office documents.

ODF may also refer to:

• OpenDocument Foundation, a defunct organization which had some interest in OpenDocument and alternative formats
• Optical distribution frame, a distribution frame device to terminate optical fiber cables

• Oregon Department of Forestry, a government agency in the U.S.
• Ombudsman for the Defence Forces, independent investigative military body in Ireland
• Open defecation free, a state of a village or community which has basic sanitation
• Operation Deep Freeze, a series of U.S. missions in Antarctica
• Orientation distribution function, in material science, a mathematical function for determining texture
• Osteoclast differentiation factor, in molecular biology, a signaling protein
• Open Dialogue Foundation, a human rights NGO in Poland