Murtaugh may refer to:

• Murtaugh, Idaho, a town in southern Idaho, USA
• Murtaugh Peak, a mountain in Antarctica
• "Murtaugh" (How I Met Your Mother), an episode of How I Met Your Mother

• Danny Murtaugh (1917–1976), American professional baseball player
• John Murtaugh (disambiguation), multiple people
• Tim Murtaugh (born 1943), American professional baseball player and manager

• Roger Murtaugh, a character in the Lethal Weapon film series
• Alexia Murtaugh, a fictional character in the webcomic Schlock Mercenary

• Murtagh
• Murdaugh