Mox or MOX may refer to:

• Mox-Linde Gases, a Malaysian manufacturer of industrial gases
• Mixed oxide fuel, used in nuclear power plants
• Power Nine § Moxes, a type of card in the Power Nine group of Magic: The Gathering cards
• Mac OS X, name of MacOS used from 2001 to 2012 (and also until 2016, when it was shortened to OS X)
• The quarterback played by James Vanderbeek in Varsity Blues (film)
• MOX (Mobitex Area Exchange), a node of the Mobitex cellular network standard
• Morris Municipal Airport, Minnesota, United States
• A 1933 novel in The Shadow pulp fiction series
• A nickname of wrestler Jonathan Good, performing as Jon Moxley
• Microsoft Open XML, a file format
• Mox Peaks, mountains in Washington State, United States
• A music workstation synthesiser in the Yamaha Motif series
• Mox McQuery (1861–1900), baseball player