Gargan may refer to:

• Edward Gargan (1902–1964), American actor
• Jack Gargan (politician), chairman of the Reform Party and candidate for the United States House of Representatives
• Jack Gargan (hurler) (1918–1991), Irish hurler
• John Gargan (disambiguation)
• Dan Gargan (born 1982), American soccer player
• Sam Gargan (born 1989), English footballer
• Mac Gargan, fictional character and most well-known incarnation of Spider-Man villain, the Scorpion

Mount Gargan has been used to describe various mountains said to have been visited by Michael the Archangel:

• Monte Gargano or San'Angelo, a mountain in Italy
• Mont Gargan, a mountain in France
• St Michael's Mount, off Cornwall in Britain