Monopole may refer to:

• Magnetic monopole, or Dirac monopole, a hypothetical particle that may be loosely described as a magnet with only one pole
• Monopole (mathematics), a connection over a principal bundle G with a section (the Higgs field) of the associated adjoint bundle
• Monopole, the first term in a multipole expansion
• Monopole (wine), an appellation owned by only one winery
• Monopole (album), a 2011 album by White Town
• Monopole antenna, a radio antenna that replaces half of a dipole antenna with a ground plane at right-angles to the remaining half
• Monopole, a tubular self-supporting telecommunications mast
• The Monopole, a bar in Plattsburgh, NY
• Établissements Monopole, a French auto parts manufacturer, racing car builder and racing team.

• Dipole, a particle with a north and south pole
• Dyon, a particle with electric and magnetic charge
• Instanton, a class of field solutions that includes monopoles
• Monomial, a polynomial which has only one term
• Monopoly (disambiguation)
• Seiberg-Witten monopole, a solution of the Seiberg-Witten equations
• 't Hooft–Polyakov monopole, analogous to Dirac monopole, but without singularities
• Wu–Yang monopole, a monopole solution of Yang-Mills equations