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The Ministry of National Defence (Arabic: وزارة الدفاع الوطني) is a government ministry office of the Republic of Tunisia, responsible for coordinating and supervising all agencies and functions of the government concerned directly with national security and the Tunisian Armed Forces. Since 2021, the Minister of National Defence has been Imed Memmich.

This is a list of defence ministers of Tunisia.

• 1956–1957: Habib Bourguiba
• 1957–1966: Bahi Ladgham
• 1966–1968: Ahmed Mestiri
• 1968: Bahi Ladgham
• 1968–1969: Mohammed Mzali
• 1969–1970: Beji Caid Essebsi
• 1970–1971: Hassib Ben Ammar
• 1971–1972: Béchir M'hedhbi
• 1972–1974: Abdallah Farhat
• 1974–1976: Hédi Khefacha
• 1976–1979: Abdallah Farhat
• 1979–1980: Rachid Sfar
• 1980–1988: Slaheddine Baly
• 1988–1991: Abdallah Kallel
• 1991: Habib Boularès
• 1991–1996: Abdelaziz Ben Dhia
• 1996–1997: Abdallah Kallel
• 1997–1999: Habib Ben Yahia
• 1999–2001: Mohamed Jegham
• 2001–2004: Dali Jazi
• 2004–2005: Hédi M'henni
• 2005–2010: Kamel Morjane
• 2010–2011: Ridha Grira
• 2011–2013: Abdelkarim Zbidi
• 2013–2014: Rachid Sabbagh
• 2014–2015: Ghazi Jeribi
• 2015–2017: Farhat Horchani
• 2017–2019: Abdelkarim Zbidi
• 2019–2020: Mohamed Karim El Jamoussi (interim)
• 2020–2021: Imed Hazgui
• 2021: Brahim Bartagi
• 2021: Imed Memmich

• Official Website of the Tunisian Ministry of Defence