Michael or Mike Pearson may refer to:

• Lester B. Pearson (1897–1972), known as Mike Pearson, 14th Prime Minister of Canada
• Michael Pearson (horologist) (born 1936), English author on the subject of clocks
• Michael Pearson (historian) (born 1941), historian of Indian Ocean
• Michael Pearson (author) (born 1949), American novelist
• Michael Pearson, 4th Viscount Cowdray (born 1944), landowner and publisher
• Mike Parker Pearson (born 1957), British archaeologist
• J. Michael Pearson (born 1960), CEO of Valeant Pharmaceuticals International
• Mike Pearson (gridiron football) (born 1980), Canadian football player
• Mike Pearson (footballer) (born 1988), Welsh association footballer

• Mike Parson (born 1955), Governor of Missouri since 2018
• Mike Person (born 1988), American football player