Mike may refer to:

• Mike (cat), cat and guardian of the British Museum
• Mike the Headless Chicken, chicken that lived for 18 months after his head had been cut off
• Mike (chimpanzee), a chimpanzee featured in several books and documentaries

• Mike (miniseries), a 2022 Hulu limited series based on the life of American boxer Mike Tyson
• Mike (2022 film), a Malayalam film produced by John Abraham
• Mike (album), an album by Mike Mohede
• Mike (1926 film), an American film
• Mike (musician), American rapper, songwriter and record producer
• Mike (novel), a 1909 novel by P. G. Wodehouse
• "Mike" (song), by Elvana Gjata and Ledri Vula featuring John Shahu
• Mike (Twin Peaks), a character from Twin Peaks
• "Mike", a song by Xiu Xiu from their 2004 album Fabulous Muscles
• mike. (musician), American rapper and baseball player formerly known as Mike Stud

• Mike (cellular network), a defunct Canadian cellular network
• Mike and Ike, a candies brand

• MIKE Force, a unit in the Vietnam War
• Ivy Mike, the first test of a full-scale thermonuclear weapon

• Microphone
• Micrometer (device)
• MIKE2.0 methodology, open source delivery methodology for enterprise information management consultants

• Mike (given name)
• The letter "M" in the NATO phonetic alphabet
• Mike, Missouri, a community in the United States
• Middle linebacker, a position in American football

• Mikee (given name)
• Mikes (disambiguation)
• Doctor Mike (disambiguation)
• Like Mike (disambiguation)
• All pages with titles containing Mike